NDFIP2 anticorps (AA 16-336)

N° du produit ABIN7871068

Cet anticorps anti-NDFIP2 Monoclonal Souris (Clone 10D6D7) (ABIN7871068) détecte spécifiquement NDFIP2 dans WB, FACS, IF et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour NDFIP2 anticorps (AA 16-336) (ABIN7871068)

Antigène: NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NDFIP2 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 10D6D7

Détail du produit anti-NDFIP2 anticorps

Épitope: AA 16-336

Fonction: NDFIP2 Antibody / NEDD4 family-interacting protein 2

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids M16-L336) was used as the immunogen for the NDFIP2 antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the NDFIP2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the NDFIP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur NDFIP2

Antigène: NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))

Autre désignation: NDFIP2

Sujet: NEDD4 family-interacting protein 2 is a protein that in humans is encoded by the NDFIP2 gene. The NEDD4 family-interacting protein 1 (NDFIP1) belongs to a small group of evolutionarily conserved proteins with three transmembrane domains and is an integral Golgi membrane protein. It is a potential target for ubiquitination by the Nedd4 family of proteins. NDFIP1 is strongly expressed in surviving neurons following acute cortical brain injury, and overexpression in cultured cortical neurons increased survival following growth factor starvation, suggesting that NDFIP1 may play a role in neuronal survival. NDFIP1 and the related protein NDFIP2 are thought to interact with and regulate multiple components of the EGF and PTEN/Akt signaling pathways. Recent studies suggest that NDFIP1 may also play a role in Th17 differentiation by limiting the production of proinflammatory cytokines.

UniProt: Q9NV92

Pathways: Negative Regulation of Transporter Activity, SARS-CoV-2 Protein Interactome