ADRA2A anticorps (AA 16-465)

N° du produit ABIN7871084

Cet anticorps Lapin Polyclonal détecte spécifiquement ADRA2A dans WB, ELISA et FACS. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour ADRA2A anticorps (AA 16-465) (ABIN7871084)

Antigène: ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADRA2A est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-ADRA2A anticorps

Épitope: AA 16-465

Fonction: ADRA2A Antibody / Alpha 2a Adrenergic Receptor

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids M16-V465) was used as the immunogen for the ADRA2A antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the ADRA2A antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the ADRA2A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur ADRA2A

Antigène: ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))

Autre désignation: ADRA2A

Sujet: The alpha-2A adrenergic receptor, also known as ADRA2A denotes the human gene encoding it. This gene is mapped to 10q25.2. Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons, the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences. Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.

UniProt: P08913

Pathways: EGFR Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Negative Regulation of Transporter Activity