PPM1F anticorps (AA 17-454)

N° du produit ABIN7871232

L’anticorps anti-PPM1F Polyclonal Lapin est utilisé pour la détection de PPM1F dans des échantillons de Humain. Il a été validé pour WB, ELISA et IF.

Aperçu rapide pour PPM1F anticorps (AA 17-454) (ABIN7871232)

Antigène: PPM1F (Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPM1F est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-PPM1F anticorps

Épitope: AA 17-454

Fonction: PPM1F Antibody / Protein phosphatase 1F / POPX2

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids E17-S454) was used as the immunogen for the PPM1F antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the PPM1F antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the PPM1F antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur PPM1F

Antigène: PPM1F (Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F))

Autre désignation: PPM1F

Sujet: Protein phosphatase 1F is an enzyme that in humans is encoded by the PPM1F gene. The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined.

UniProt: P49593

Pathways: Positive Regulation of Endopeptidase Activity