PIK3R5 anticorps (AA 170-864)
Aperçu rapide pour PIK3R5 anticorps (AA 170-864) (ABIN7871254)
Antigène
Voir toutes PIK3R5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 170-864
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Fonction
- PIK3R5 Antibody
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Purification
- Antigen affinity chromatography
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Immunogène
- An E.coli-derived human recombinant protein (amino acids E170-L864) was used as the immunogen for the PIK3R5 antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the PIK3R5 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the PIK3R5 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PIK3R5 (Phosphoinositide-3-Kinase, Regulatory Subunit 5 (PIK3R5))
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Autre désignation
- PIK3R5
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Sujet
- Phosphoinositide 3-kinase regulatory subunit 5 is an enzyme that in humans is encoded by the PIK3R5 gene. Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found.
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UniProt
- Q8WYR1
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Pathways
- Signalisation PI3K-Akt, Inositol Metabolic Process, Hepatitis C, VEGF Signaling
Antigène
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