Tec Protein Tyrosine Kinase (TEC) (AA 175-205) anticorps
Aperçu rapide pour Tec Protein Tyrosine Kinase (TEC) (AA 175-205) anticorps (ABIN7871303)
Antigène
Voir toutes Tec Protein Tyrosine Kinase (TEC) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 175-205
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Fonction
- TEC Antibody
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Purification
- Antigen affinity purified
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Immunogène
- A portion of amino acids 175-205 from the human protein was used as the immunogen for the TEC antibody.
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Isotype
- Ig Fraction
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Indications d'application
- The stated application concentrations are suggested starting points. Titration of the TEC antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the TEC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Tec Protein Tyrosine Kinase (TEC)
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Autre désignation
- TEC
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Sujet
- TEC belongs to the TEC subfamily of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. TEC family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. TEC kinase is an integral component of T cell signaling and has a distinct role in T cell activation. TEC may be associated with myelodysplastic syndrome.
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UniProt
- P42680
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Pathways
- Fc-epsilon Receptor Signaling Pathway
Antigène
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