CTLA4 anticorps (AA 182-210)
Aperçu rapide pour CTLA4 anticorps (AA 182-210) (ABIN7871464)
Antigène
Voir toutes CTLA4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 182-210
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Fonction
- CTLA4 Antibody / Cytotoxic T-lymphocyte protein 4 / CD152
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Purification
- Antigen affinity
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Immunogène
- A portion of amino acids 182-210 from the human protein was used as the immunogen for this CTLA4 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the CTLA4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Aliquot the CTLA4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
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Autre désignation
- CTLA4
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Sujet
- CTLA4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer.
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UniProt
- P16410
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Pathways
- Cancer Immune Checkpoints
Antigène
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