BAP1 anticorps (AA 191-326)

N° du produit ABIN7871663

Cet anticorps Souris Monoclonal détecte spécifiquement BAP1 dans ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour BAP1 anticorps (AA 191-326) (ABIN7871663)

Antigène: BAP1 (BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BAP1 est non-conjugé

Application: ELISA

Clone: BAP1-2665

Détail du produit anti-BAP1 anticorps

Épitope: AA 191-326

Fonction: BAP1 Antibody

Purification: Protein G affinity chromatography

Immunogène: A portion of amino acids 191-326 from the human protein was used as the immunogen for the BAP1 antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the BAP1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the BAP1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur BAP1

Antigène: BAP1 (BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1))

Autre désignation: BAP1

Sujet: The BAP1 gene belongs to the ubiquitin C-terminal hydrolase subfamily of de-ubiquitination enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germ line mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, Uveal melanoma and cutaneous melanoma.

UniProt: Q92560