METAP2 anticorps (AA 191-464)

N° du produit ABIN7871667

L’anticorps anti-METAP2 Polyclonal Lapin est utilisé pour la détection de METAP2 dans des échantillons de Poisson zèbre (Danio rerio). Il a été validé pour WB et IHC (p).

Aperçu rapide pour METAP2 anticorps (AA 191-464) (ABIN7871667)

Antigène: METAP2 (Methionyl Aminopeptidase 2 (METAP2))

Reactivité: Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp METAP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-METAP2 anticorps

Épitope: AA 191-464

Fonction: Zebrafish Metap2 Antibody / Methionine aminopeptidase 2 / Isoforms a & b

Purification: Antigen affinity chromatography

Immunogène: An E.coli-derived zebrafish Metap2a/b recombinant protein (amino acids E191-R464) was used as the immunogen for the Zebrafish Metap2 antibody. This antibody will detect the a and b isoforms.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal dilution of the Zebrafish Metap2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Zebrafish Metap2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur METAP2

Antigène: METAP2 (Methionyl Aminopeptidase 2 (METAP2))

Autre désignation: Metap2

Sujet: Methionine aminopeptidase 2 is an enzyme that in humans is encoded by the METAP2 gene. The protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 2. Several transcript variants encoding different isoforms have been found for this gene.

UniProt: A5WVX8

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling