MYBL1 anticorps (AA 199-752)
Aperçu rapide pour MYBL1 anticorps (AA 199-752) (ABIN7871757)
Antigène
Voir toutes MYBL1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 199-752
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Fonction
- Myb-related protein A Antibody / A-Myb / MYBL1
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Purification
- Antigen affinity purified
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Immunogène
- Recombinant human protein (amino acids K199-L752) was used as the immunogen for the Myb-related protein A antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the Myb-related protein A antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the Myb-related protein A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- MYBL1 (Myb-Like Protein 1 (MYBL1))
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Autre désignation
- Myb-related protein A
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Sujet
- Myb-related protein A is a protein that in humans is encoded by the MYBL1 gene. A-Myb is expressed at specific times in reproductive tissues, some neural cells, and a subset of normal and neoplastic B lymphocytes. Both A-Myb and B-Myb are expressed in t(14:18) lymphoma cells where they then inhibit cell arrest and apoptotic signaling. Expression of B-Myb rescues cells from p53-induced G1 phase arrest that is mediated by p21, while A-Myb functions as an anti-apoptotic factor by effectively activating the bcl-2 promoter and thereby up-regulating Bcl-2 expression.
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UniProt
- P10243
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Pathways
- Cycle Cellulaire, Chromatin Binding
Antigène
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