CFHR5 anticorps (AA 203-231)

N° du produit ABIN7872079

Cet anticorps anti-CFHR5 Polyclonal Lapin (ABIN7872079) détecte spécifiquement CFHR5 dans WB, FACS et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CFHR5 anticorps (AA 203-231) (ABIN7872079)

Antigène: CFHR5 (Complement Factor H-Related 5 (CFHR5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CFHR5 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CFHR5 anticorps

Épitope: AA 203-231

Fonction: FHR-5 Antibody / Complement factor H-related protein 5 / CFHR5

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 203-231 from the human protein was used as the immunogen for the FHR-5 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the FHR-5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the FHR-5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur CFHR5

Antigène: CFHR5 (Complement Factor H-Related 5 (CFHR5))

Autre désignation: FHR-5

Sujet: CFHR5 / FHR-5 is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS). [provided by RefSeq].

UniProt: Q9BXR6