YWHAB anticorps (AA 217-246)

N° du produit ABIN7872246

L’anticorps anti-YWHAB Polyclonal Lapin est utilisé pour la détection de YWHAB dans des échantillons de Humain. Il a été validé pour WB, IF et IHC (p).

Aperçu rapide pour YWHAB anticorps (AA 217-246) (ABIN7872246)

Antigène: YWHAB (14-3-3 alpha + beta (YWHAB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp YWHAB est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-YWHAB anticorps

Épitope: AA 217-246

Fonction: YWHAB Antibody / 14-3-3 beta/alpha

Purification: Purified

Immunogène: A portion of amino acids 217-246 from the human protein was used as the immunogen for the YWHAB antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the YWHAB antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the YWHAB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur YWHAB

Antigène: YWHAB (14-3-3 alpha + beta (YWHAB))

Autre désignation: YWHAB

Sujet: YWHAB belongs to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for the gene. Both variants encode the same protein, however, they are differentially expressed in hematopoietic cells.

UniProt: P31946

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, Maintenance of Protein Location