FcRn anticorps (AA 24-215)

N° du produit ABIN7872675

L’anticorps anti-FcRn Monoclonal Souris est utilisé pour la détection de FcRn dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour FcRn anticorps (AA 24-215) (ABIN7872675)

Antigène: FcRn (neonatal Fc Receptor (FcRn))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FcRn est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: FCGRT-2932

Détail du produit anti-FcRn anticorps

Épitope: AA 24-215

Fonction: FCGRT Antibody / FcRn

Purification: Protein G affinity chromatography

Immunogène: A recombinant human partial protein (amino acids 24-215) was used as the immunogen for the FCGRT antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the FCGRT antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the FCGRT antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur FcRn

Antigène: FcRn (neonatal Fc Receptor (FcRn))

Autre désignation: FCGRT

Sujet: This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. FCGRT is present in the intestinal epithelium of neonates and mediates the selective uptake of immunoglobulin G (IgG) in mothers' milk, thereby helping newborn to acquire passive immunity. FCGRT is comprised of a heavy chain and -2-Microglobulin. FCGRT localizes in endosomes of vascular endothelial cells and selectively recycles IgG to the cell surface, thus protecting IgG from lysosomal degradation.

UniProt: P55899

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process