Recombinant ADRP anticorps (AA 249-376)

N° du produit ABIN7872821

Cet anticorps Souris Monoclonal détecte spécifiquement ADRP dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant ADRP anticorps (AA 249-376) (ABIN7872821)

Antigène: ADRP (PLIN2) (Perilipin 2 (PLIN2))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ADRP est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RADFP-9321

Détail du produit anti-ADRP anticorps

Épitope: AA 249-376

Fonction: Adipose differentiation-related protein Antibody / ADRP / Adipophilin / Perilipin 2

Purification: Protein A/G affinity

Immunogène: A recombinant fragment (within amino acids 249-376) of human Adipophilin protein was used as the immunogen for the Adipose differentiation-related protein antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the Adipose differentiation-related protein antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Adipose differentiation-related protein antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur ADRP

Antigène: ADRP (PLIN2) (Perilipin 2 (PLIN2))

Autre désignation: Adipose differentiation-related protein

Sujet: Recognizes a protein of 48 kDa, which is identified as Adipophilin. It belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.

UniProt: Q99541

Pathways: Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism