RNASEH2A anticorps (AA 25-299)

N° du produit ABIN7872867

L’anticorps anti-RNASEH2A Polyclonal Lapin est utilisé pour la détection de RNASEH2A dans des échantillons de Humain. Il a été validé pour WB, ELISA et FACS.

Aperçu rapide pour RNASEH2A anticorps (AA 25-299) (ABIN7872867)

Antigène: RNASEH2A (Ribonuclease H2, Subunit A (RNASEH2A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNASEH2A est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-RNASEH2A anticorps

Épitope: AA 25-299

Fonction: RNase H2 subunit A Antibody / RNASEH2A

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids R25-L299) was used as the immunogen for the RNase H2 subunit A antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the RNase H2 subunit A antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the RNase H2 subunit A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur RNASEH2A

Antigène: RNASEH2A (Ribonuclease H2, Subunit A (RNASEH2A))

Autre désignation: RNase H2 subunit A

Sujet: Ribonuclease H2 subunit A, also known as RNase H2 subunit A, is an enzyme that in humans is encoded by the RNASEH2A gene. The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.

UniProt: O75792