Metabotropic Glutamate Receptor 1 anticorps (AA 25-466)

N° du produit ABIN7872881

Cet anticorps Lapin Polyclonal détecte spécifiquement Metabotropic Glutamate Receptor 1 dans WB, ELISA, IHC (p) et FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Metabotropic Glutamate Receptor 1 anticorps (AA 25-466) (ABIN7872881)

Antigène: Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Metabotropic Glutamate Receptor 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-Metabotropic Glutamate Receptor 1 anticorps

Épitope: AA 25-466

Fonction: mGluR1 Antibody / GRM1

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids R25-E466) was used as the immunogen for the mGluR1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the mGluR1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the mGluR1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Metabotropic Glutamate Receptor 1

Antigène: Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))

Autre désignation: mGluR1

Sujet: The GRM1 gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: Q13255