DNMT3B anticorps (AA 258-472)

N° du produit ABIN7872975

L’anticorps anti-DNMT3B Polyclonal Lapin est utilisé pour la détection de DNMT3B dans des échantillons de Humain, Souris, Rat et Singe. Il a été validé pour WB, ELISA et FACS.

Aperçu rapide pour DNMT3B anticorps (AA 258-472) (ABIN7872975)

Antigène: DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DNMT3B est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-DNMT3B anticorps

Épitope: AA 258-472

Fonction: DNMT3b Antibody

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids M258-D472) was used as the immunogen for the DNMT3b antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the DNMT3b antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the DNMT3b antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur DNMT3B

Antigène: DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))

Autre désignation: DNMT3b

Sujet: DNA (cytosine-5-)-methyltransferase 3 beta, is an enzyme that in humans in encoded by the DNMT3B gene. CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.

UniProt: Q9UBC3