IL-11 anticorps (AA 27-61)

N° du produit ABIN7873137

L’anticorps anti-IL-11 Polyclonal Lapin est utilisé pour la détection de IL-11 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour IL-11 anticorps (AA 27-61) (ABIN7873137)

Antigène: IL-11 (IL11) (Interleukin 11 (IL11))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-11 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IL-11 anticorps

Épitope: AA 27-61

Fonction: IL-11 Antibody (N-Terminal Region)

Purification: Antigen affinity

Immunogène: A portion of amino acids 27-61 from human IL-11 was used as the immunogen for the IL-11 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the IL-11 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the IL-11 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur IL-11

Antigène: IL-11 (IL11) (Interleukin 11 (IL11))

Autre désignation: IL-11

Sujet: Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed: 2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:< a href=http://www.uniprot.org/citations/12919066 target=_blank>12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. [UniProt]

UniProt: P20809

Pathways: Signalistation JAK/STAT, Negative Regulation of Hormone Secretion