WFS1 anticorps (AA 272-876)

N° du produit ABIN7873171

Cet anticorps anti-WFS1 Polyclonal Lapin (ABIN7873171) détecte spécifiquement WFS1 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour WFS1 anticorps (AA 272-876) (ABIN7873171)

Antigène: WFS1 (Wolfram Syndrome 1 (WFS1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WFS1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-WFS1 anticorps

Épitope: AA 272-876

Fonction: WFS1 Antibody / Wolframin

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids D272-K876) was used as the immunogen for the WFS1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the WFS1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the WFS1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur WFS1

Antigène: WFS1 (Wolfram Syndrome 1 (WFS1))

Autre désignation: WFS1

Sujet: Wolframin is a protein that in humans is encoded by the WFS1 gene. This gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system. Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6), also known as DFNA14 or DFNA38. Alternatively spliced transcript variants have been found for this gene.

UniProt: O76024

Pathways: Sensory Perception of Sound, Carbohydrate Homeostasis, ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome