Mesothelin anticorps (AA 273-407)

N° du produit ABIN7873175

Cet anticorps Souris Monoclonal détecte spécifiquement Mesothelin dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Mesothelin anticorps (AA 273-407) (ABIN7873175)

Antigène: Mesothelin (MSLN)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Mesothelin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: MSLN-3385

Détail du produit anti-Mesothelin anticorps

Épitope: AA 273-407

Fonction: Mesothelin Antibody / MSLN

Purification: Protein G affinity chromatography

Immunogène: A portion of amino acids 273-407 from the human protein was used as the immunogen for the Mesothelin antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the Mesothelin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Mesothelin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Mesothelin

Antigène: Mesothelin (MSLN)

Autre désignation: Mesothelin

Sujet: Mesothelin is a 40 kDa glycosyl-phosphatidylinositol-anchored glycoprotein cleaved from a 69 kDa precursor protein. Mesothelin immunoreactivity is high in cancers of the ovary (serous papillary, endometrioid and undifferentiated) and pancreas, with less frequent staining seen in adenocarcinomas of the endometrium, lung and stomach/esophagus. Mesothelin is one of the most sensitive markers for mesothelioma.

UniProt: Q13421

Pathways: EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process