EPH Receptor B2 anticorps (AA 278-540)

N° du produit ABIN7873215

L’anticorps anti-EPH Receptor B2 Polyclonal Lapin est utilisé pour la détection de EPH Receptor B2 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, FACS et IF.

Aperçu rapide pour EPH Receptor B2 anticorps (AA 278-540) (ABIN7873215)

Antigène: EPH Receptor B2 (EPHB2)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPH Receptor B2 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Détail du produit anti-EPH Receptor B2 anticorps

Épitope: AA 278-540

Fonction: EPHB2 Antibody / Eph receptor B2

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids K278-K540) was used as the immunogen for the EPHB2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the EPHB2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the EPHB2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur EPH Receptor B2

Antigène: EPH Receptor B2 (EPHB2)

Autre désignation: EPHB2

Sujet: Ephrin type-B receptor 2 is a protein that in humans is encoded by the EPHB2 gene. This gene is mapped to 1p36.12. This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants.

UniProt: P29323

Pathways: Signalisation RTK, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins