Poliovirus Receptor anticorps (AA 28-331)

N° du produit ABIN7873259

Cet anticorps Souris Monoclonal détecte spécifiquement Poliovirus Receptor dans WB, FACS et IHC (p). Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour Poliovirus Receptor anticorps (AA 28-331) (ABIN7873259)

Antigène: Poliovirus Receptor (PVR)

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Poliovirus Receptor est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 5I13D1

Détail du produit anti-Poliovirus Receptor anticorps

Épitope: AA 28-331

Fonction: Poliovirus Receptor Antibody / PVR

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids D28-E331) was used as the immunogen for the Poliovirus Receptor antibody.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal dilution of the Poliovirus Receptor antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Poliovirus Receptor antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Poliovirus Receptor

Antigène: Poliovirus Receptor (PVR)

Autre désignation: Poliovirus Receptor

Sujet: CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that in humans is encoded by the PVR gene. The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: P15151

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome