Poliovirus Receptor anticorps (AA 28-331)

N° du produit ABIN7873260

L’anticorps anti-Poliovirus Receptor Monoclonal Souris est utilisé pour la détection de Poliovirus Receptor dans des échantillons de Humain et Souris. Il a été validé pour WB et IHC (p).

Aperçu rapide pour Poliovirus Receptor anticorps (AA 28-331) (ABIN7873260)

Antigène: Poliovirus Receptor (PVR)

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Poliovirus Receptor est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 9B9F1

Détail du produit anti-Poliovirus Receptor anticorps

Épitope: AA 28-331

Fonction: Poliovirus Receptor Antibody / CD155 / PVR

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids D28-E331) was used as the immunogen for the Poliovirus Receptor antibody.

Isotype: IgG1

Information d'application

Indications d'application: Optimal dilution of the Poliovirus Receptor antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Poliovirus Receptor antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Poliovirus Receptor

Antigène: Poliovirus Receptor (PVR)

Autre désignation: Poliovirus Receptor

Sujet: CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that in humans is encoded by the PVR gene. The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: P15151

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome