RNF8 anticorps (AA 3-488)
Aperçu rapide pour RNF8 anticorps (AA 3-488) (ABIN7873547)
Antigène
Voir toutes RNF8 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 3-488
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Fonction
- Rnf8 Antibody
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Purification
- Affinity purified
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Immunogène
- Recombinant mouse protein (amino acids E3-S488) was used as the immunogen for the Rnf8 antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the Rnf8 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the Rnf8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- RNF8 (Ring Finger Protein 8 (RNF8))
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Autre désignation
- Rnf8
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Sujet
- E3 ubiquitin-protein ligase RNF8 is an enzyme that in humans is encoded by the RNF8 gene. The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants.
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UniProt
- Q8VC56
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Pathways
- Production of Molecular Mediator of Immune Response
Antigène
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