HGS anticorps (AA 3-777)

N° du produit ABIN7873551

L’anticorps anti-HGS Polyclonal Lapin est utilisé pour la détection de HGS dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IF, FACS, IP et IHC (p).

Aperçu rapide pour HGS anticorps (AA 3-777) (ABIN7873551)

Antigène: HGS (Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HGS est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-HGS anticorps

Épitope: AA 3-777

Fonction: HGS Antibody / HRS / HGF-regulated tyrosine kinase substrate

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids R3-D777) was used as the immunogen for the HGS antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the HGS antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the HGS antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur HGS

Antigène: HGS (Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS))

Autre désignation: HGS

Sujet: Hepatocyte growth factor-regulated tyrosine kinase substrate is an enzyme that in humans is encoded by the HGS gene. It is mapped to 17q25.3. The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation.

UniProt: O14964

Pathways: EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Synaptic Vesicle Exocytosis, EGFR Downregulation