HRS (HRS) (AA 3-777) anticorps

N° du produit ABIN7873552

Cet anticorps anti-HRS Monoclonal Souris (Clone 4B7E2) (ABIN7873552) détecte spécifiquement HRS dans WB, IF, FACS et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour HRS (HRS) (AA 3-777) anticorps (ABIN7873552)

Antigène: HRS

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 4B7E2

Détail du produit

Épitope: AA 3-777

Fonction: HGF-regulated tyrosine kinase substrate Antibody / HRS / HGS

Purification: Antigen affinity purified

Immunogène: Recombinant human HGS protein (amino acids R3-D777) was used as the immunogen for the HGF-regulated tyrosine kinase substrate antibody.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal dilution of the HGF-regulated tyrosine kinase substrate antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the HGF-regulated tyrosine kinase substrate antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détail du antigène

Antigène: HRS

Autre désignation: HGF-regulated tyrosine kinase substrate

Sujet: Hepatocyte growth factor-regulated tyrosine kinase substrate is an enzyme that in humans is encoded by the HGS gene. It is mapped to 17q25.3. The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation.

UniProt: O14964

Pathways: CXCR4-mediated Signaling Events, EGFR Downregulation