Cadherin-16 anticorps (AA 300-600)

N° du produit ABIN7873680

L’anticorps anti-Cadherin-16 Monoclonal Souris est utilisé pour la détection de Cadherin-16 dans des échantillons de Humain. Il a été validé pour WB et IHC (p).

Aperçu rapide pour Cadherin-16 anticorps (AA 300-600) (ABIN7873680)

Antigène: Cadherin-16 (CDH16)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cadherin-16 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: CDH16-2449

Détail du produit anti-Cadherin-16 anticorps

Épitope: AA 300-600

Fonction: Cadherin 16 Antibody / CDH16 (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 300-600) from the human protein was used as the immunogen for the Cadherin 16 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the Cadherin 16 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the Cadherin 16 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Cadherin-16

Antigène: Cadherin-16 (CDH16)

Autre désignation: Cadherin 16

Sujet: This mAb recognizes a protein of 130 kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.

UniProt: O75309