MYBL2 anticorps (AA 31-695)

N° du produit ABIN7873801

Cet anticorps anti-MYBL2 Polyclonal Lapin (ABIN7873801) détecte spécifiquement MYBL2 dans WB, ELISA, IF et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour MYBL2 anticorps (AA 31-695) (ABIN7873801)

Antigène: MYBL2 (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYBL2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-MYBL2 anticorps

Épitope: AA 31-695

Fonction: B-Myb Antibody / Myb-related protein B / MYBL2

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids K31-R695) was used as the immunogen for the B-Myb antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the B-Myb antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the B-Myb antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur MYBL2

Antigène: MYBL2 (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2))

Autre désignation: B-Myb

Sujet: Myb-related protein B is a protein that in humans is encoded by the MYBL2 gene. The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. Barletta et al.(1991) assigned the MYBL2 gene to chromosome Xq13. However, Noben-Trauth et al.(1996) demonstrated that this assignment was an error. Using mouse Mybl2 cDNA clones as probes, they assigned Mybl2 in an interspecific backcross panel to distal mouse chromosome 2. Using human cDNA probes in combination with fluorescence in situ hybridization analysis, they localized MYBL2 to chromosome 20q13.1, a region that is commonly deleted in myeloid disorders and shows high homology of synteny to mouse chromosome 2. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined.

UniProt: P10244

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases, Chromatin Binding