Glypican 3 anticorps (AA 32-535)

N° du produit ABIN7873927

Cet anticorps anti-Glypican 3 Polyclonal Lapin (ABIN7873927) détecte spécifiquement Glypican 3 dans FACS, WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour Glypican 3 anticorps (AA 32-535) (ABIN7873927)

Antigène: Glypican 3 (GPC3)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glypican 3 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), ELISA

Détail du produit anti-Glypican 3 anticorps

Épitope: AA 32-535

Fonction: Glypican 3 Antibody

Purification: Affinity purified

Immunogène: A human recombinant protein (amino acids D32-A535) was used as the immunogen for the Glypican 3 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Glypican 3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Glypican 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Glypican 3

Antigène: Glypican 3 (GPC3)

Autre désignation: Glypican 3

Sujet: Glypican-3 is a protein that, in humans, is encoded by the GPC3 gene. It is mapped to Xq26.2. Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.

UniProt: P51654

Pathways: Glycosaminoglycan Metabolic Process