Klotho anticorps (AA 331-365)

N° du produit ABIN7874025

L’anticorps anti-Klotho Polyclonal Lapin est utilisé pour la détection de Klotho dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour Klotho anticorps (AA 331-365) (ABIN7874025)

Antigène: Klotho (KL)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Klotho est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Klotho anticorps

Épitope: AA 331-365

Fonction: Klotho Antibody (Center Region)

Purification: Antigen affinity

Immunogène: A portion of amino acids 331-365 from human Klotho was used as the immunogen for the Klotho antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the Klotho antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Klotho antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Klotho

Antigène: Klotho (KL)

Autre désignation: Klotho

Sujet: May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 239 and 872, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D (By similarity). Essential factor for the specific interaction between FGF23 and FGFR1 (By similarity). [UniProt]

UniProt: Q9UEF7

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hormone Activity, Growth Factor Binding