Recombinant Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) anticorps

N° du produit ABIN7874272

Cet anticorps anti-Spectrin, Beta, Non-erythrocytic 2 Monoclonal Souris (Clone rSPTBN2-1778) (ABIN7874272) détecte spécifiquement Spectrin, Beta, Non-erythrocytic 2 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) anticorps (ABIN7874272)

Antigène: Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), ELISA

Clone: RSPTBN2-1778

Détail du produit

Épitope: AA 356-475

Fonction: Recombinant Spectrin beta III Antibody / SPTBN2

Purification: Protein G affinity chromatography

Immunogène: A recombinant human partial protein (amino acids 356-475) was used as the immunogen for the recombinant Spectrin beta III antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant Spectrin beta III antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the recombinant Spectrin beta III antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détail du antigène

Antigène: Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)

Autre désignation: Spectrin beta III

Sujet: Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I/alpha-II) four beta-subunits (beta-I-beta-IV) and a beta-H subunit creating diversity and specialization of function. Spectrin and spectrin are present in erythrocytes, whereas spectrin II (also designated fodrin ) and spectrin I (also designated fodrin ) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Spectrin III is highly homologous to both spectrin I and spectrin II. Spectrin III is highly expressed in brain, kidney, pancreas and liver, and at lower levels in lung and placenta. Spectrin beta 3 is primarily expressed in nervous tissues with highest expression levels in the cerebellum, where it is found in Purkinje cell soma and dendrites.

UniProt: O15020

Pathways: Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis