Angiopoietin 2 anticorps (AA 357-404)

N° du produit ABIN7874276

Cet anticorps Lapin Polyclonal détecte spécifiquement Angiopoietin 2 dans WB, ELISA, IF, IHC (p) et FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Angiopoietin 2 anticorps (AA 357-404) (ABIN7874276)

Antigène: Angiopoietin 2 (ANGPT2)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Angiopoietin 2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-Angiopoietin 2 anticorps

Épitope: AA 357-404

Fonction: ANGPT2 Antibody / Angiopoietin-2 / ANG2

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids N357-K404) was used as the immunogen for the ANGPT2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the ANGPT2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the ANGPT2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Angiopoietin 2

Antigène: Angiopoietin 2 (ANGPT2)

Autre désignation: ANGPT2

Sujet: ANGPT2, also known as ANG2 or Angiopoietin 2, is a protein that in humans is encoded by the ANGPT2 gene. It is mapped to 8p23.1. ANGPT2 is a naturally occurring antagonist of ANG1 that competes for binding to the TIE2 receptor and blocks ANGPT1-induced TIE2 autophosphorylation during vasculogenesis. The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. ANGPT2 was significantly increased in plasma and alveolar edema fluid in adults with acute lung injury compared to controls or patients with hydrostatic pulmonary edema, tracheal. ANGPT2 was also significantly increased in neonates with respiratory distress syndrome who developed bronchopulmonary edema. It is also a mediator of epithelial necrosis with an important role in hyperoxic acute lung injury and pulmonary edema.

UniProt: O15123

Pathways: Signalisation RTK