Cadherin-16 anticorps (AA 371-507)

N° du produit ABIN7874426

Cet anticorps Souris Monoclonal détecte spécifiquement Cadherin-16 dans ELISA et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Cadherin-16 anticorps (AA 371-507) (ABIN7874426)

Antigène: Cadherin-16 (CDH16)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cadherin-16 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CDH16-2448

Détail du produit anti-Cadherin-16 anticorps

Épitope: AA 371-507

Fonction: CDH16 Antibody / Cadherin 16

Purification: Protein G affinity chromatography

Immunogène: A recombinant human partial protein (amino acids 371-507) was used as the immunogen for the CDH16 antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the CDH16 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the CDH16 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Cadherin-16

Antigène: Cadherin-16 (CDH16)

Autre désignation: CDH16

Sujet: This MAb recognizes a protein of 130 kDa, identified as Ksp-cadherin (also called CDH16 and Cadherin 16). Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.

UniProt: O75309