HTR2C anticorps (AA 372-458)

N° du produit ABIN7874430

L’anticorps anti-HTR2C Polyclonal Lapin est utilisé pour la détection de HTR2C dans des échantillons de Humain et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour HTR2C anticorps (AA 372-458) (ABIN7874430)

Antigène: HTR2C (5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HTR2C est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-HTR2C anticorps

Épitope: AA 372-458

Fonction: 5-HT2C Receptor Antibody / HTR2C

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids N372-V458) was used as the immunogen for the 5-HT2C Receptor antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the 5-HT2C Receptor antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the 5-HT2C Receptor antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur HTR2C

Antigène: HTR2C (5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))

Autre désignation: 5-HT2C Receptor

Sujet: This gene encodes a seven-transmembrane G-protein-coupled receptor. The encoded protein responds to signaling through the neurotransmitter serotonin. The mRNA of this gene is subject to multiple RNA editing events, where adenosine residues encoded by the genome are converted to inosines. RNA editing is predicted to alter the structure of the second intracellular loop, thereby generating alternate protein forms with decreased ability to interact with G proteins. Abnormalities in RNA editing of this gene have been detected in victims of suicide that suffer from depression. In addition, naturally-occuring variation in the promoter and 5' non-coding and coding regions of this gene may show statistically-significant association with mental illness and behavioral disorders. Alternative splicing results in multiple different transcript variants.

UniProt: P28335

Pathways: Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour