SOCS5 anticorps (AA 386-536)

N° du produit ABIN7874548

Cet anticorps anti-SOCS5 Polyclonal Lapin (ABIN7874548) détecte spécifiquement SOCS5 dans WB, ELISA et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SOCS5 anticorps (AA 386-536) (ABIN7874548)

Antigène: SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOCS5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-SOCS5 anticorps

Épitope: AA 386-536

Fonction: SOCS5 Antibody / Suppressor of cytokine signaling 5

Purification: Antigen affinity purified

Immunogène: Amino acids M386-K536 from the human protein were used as the immunogen for the SOCS5 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the SOCS5 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the SOCS5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur SOCS5

Antigène: SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))

Autre désignation: SOCS5

Sujet: SOCS5 (Suppressor of cytokine signaling 5) is a member of the SOCS family, a group of intracellular proteins that function as negative regulators of cytokine receptor signaling. SOCS5 contains an SH2 domain and a SOCS box motif, allowing it to interact with activated receptors and associated kinases to modulate JAK-STAT pathway activity. By preventing excessive cytokine signaling, SOCS5 maintains immune system balance and contributes to cellular homeostasis. A SOCS5 antibody is a valuable tool for investigating these regulatory mechanisms.

SOCS5 has been implicated in the regulation of interleukin and growth factor signaling. Its activity helps control cell proliferation, differentiation, and survival. Aberrant expression or dysfunction of SOCS5 has been associated with various pathological conditions, including chronic inflammation, autoimmune disorders, and certain cancers. Using a SOCS5 antibody enables researchers to evaluate its expression patterns, molecular interactions, and role in disease development.

In addition to its role in immune regulation, SOCS5 has been shown to influence neural development and epithelial cell signaling, highlighting its multifunctional nature. Studies have indicated that SOCS5 can act as a tumor suppressor in specific contexts, while in other cases, it may contribute to oncogenesis depending on the signaling environment. Employing a SOCS5 antibody allows for precise characterization of these complex roles across different biological systems.

NSJ Bioreagents offers a high-quality SOCS5 antibody validated for applications such as western blot, immunohistochemistry, and immunofluorescence. Selecting a SOCS5 antibody from NSJ Bioreagents ensures reliable performance for studies of cytokine signaling, immune regulation, and cancer biology.

UniProt: O75159

Pathways: Signalistation JAK/STAT, EGFR Signaling Pathway, Positive Regulation of Immune Effector Process