Mesothelin anticorps (AA 44-497)

N° du produit ABIN7875019

Cet anticorps anti-Mesothelin Polyclonal Lapin (ABIN7875019) détecte spécifiquement Mesothelin dans WB et ELISA. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour Mesothelin anticorps (AA 44-497) (ABIN7875019)

Antigène: Mesothelin (MSLN)

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Mesothelin est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Mesothelin anticorps

Épitope: AA 44-497

Fonction: Msln Antibody / Mesothelin

Purification: Antigen affinity purified

Immunogène: An E.coli-derived mouse recombinant protein (Q44-K497) was used as the immunogen for the Msln antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Msln antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Msln antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Mesothelin

Antigène: Mesothelin (MSLN)

Autre désignation: Msln

Sujet: Mesothelin, also known as MSLN or MPF, is a protein that in humans is encoded by the MSLN gene. This gene is mapped to 16p13.3. This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas.

UniProt: Q61468

Pathways: EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process