ChT anticorps (AA 446-580)

N° du produit ABIN7875049

Cet anticorps anti-ChT Polyclonal Lapin (ABIN7875049) détecte spécifiquement ChT dans WB, FACS et ELISA. L’anticorps est réactif avec des échantillons de Souris, Humain et Rat.

Aperçu rapide pour ChT anticorps (AA 446-580) (ABIN7875049)

Antigène: ChT (High Affinity Choline Transporter (ChT))

Reactivité: Souris, Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ChT est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Détail du produit anti-ChT anticorps

Épitope: AA 446-580

Fonction: SLC5A7 Antibody / High affinity choline transporter 1

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids R446-Q580) was used as the immunogen for the SLC5A7 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the SLC5A7 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the SLC5A7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur ChT

Antigène: ChT (High Affinity Choline Transporter (ChT))

Autre désignation: SLC5A7

Sujet: The high-affinity choline transporter (ChT) also known as solute carrier family 5 member 7 is a protein in humans that is encoded by the SLC5A7 gene. This gene encodes a sodium ion- and chloride ion-dependent high-affinity transporter that mediates choline uptake for acetylcholine synthesis in cholinergic neurons. The protein transports choline from the extracellular space into presynaptic terminals for synthesis into acetylcholine. Increased choline uptake results from increased density of this protein in synaptosomal plasma membranes in response to depolarization of cholinergic terminals. Dysfunction of cholinergic signaling has been implicated in various disorders including depression, attention-deficit disorder, and schizophrenia. An allelic variant of this gene is associated with autosomal dominant distal hereditary motor neuronopathy type VIIA. Alternative splicing results in multiple transcript variants.

UniProt: Q9GZV3