IDE anticorps (AA 464-735)

N° du produit ABIN7875138

L’anticorps anti-IDE Polyclonal Lapin est utilisé pour la détection de IDE dans des échantillons de Poisson zèbre (Danio rerio). Il a été validé pour WB et IHC (p).

Aperçu rapide pour IDE anticorps (AA 464-735) (ABIN7875138)

Antigène: IDE (Insulin-Degrading Enzyme (IDE))

Reactivité: Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IDE est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-IDE anticorps

Épitope: AA 464-735

Fonction: Zebrafish Ide Antibody / Insulin degrading enzyme

Purification: Antigen affinity chromatography

Immunogène: An E.coli-derived zebrafish Ide recombinant protein (amino acids F464-K735) was used as the immunogen for the Zebrafish Ide antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal dilution of the Zebrafish Ide antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Zebrafish Ide antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur IDE

Antigène: IDE (Insulin-Degrading Enzyme (IDE))

Autre désignation: Ide

Sujet: Insulin-degrading enzyme, also known as IDE, is a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signaling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causative for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Pathways: SARS-CoV-2 Protein Interactome