DNMT1 anticorps (AA 509-1577)

N° du produit ABIN7875507

L’anticorps anti-DNMT1 Polyclonal Lapin est utilisé pour la détection de DNMT1 dans des échantillons de Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour DNMT1 anticorps (AA 509-1577) (ABIN7875507)

Antigène: DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DNMT1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-DNMT1 anticorps

Épitope: AA 509-1577

Fonction: DNA methyltransferase 1 Antibody / Dnmt1

Purification: Antigen affinity purified

Immunogène: Recombinant mouse protein (amino acids Q509-Q1577) was used as the immunogen for the DNA methyltransferase 1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the DNA methyltransferase 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the DNA methyltransferase 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur DNMT1

Antigène: DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))

Autre désignation: DNA methyltransferase 1

Sujet: DNA (cytosine-5)-methyltransferase 1 is an enzyme that in humans is encoded by the DNMT1 gene. This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.

UniProt: P13864

Pathways: SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2