Glypican 3 anticorps (AA 511-580) (CF®555)

N° du produit ABIN7875532

Cet anticorps anti-Glypican 3 Monoclonal Souris conjugué à CF®555 (Clone SPM595) (ABIN7875532) détecte spécifiquement Glypican 3 dans FACS et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Glypican 3 anticorps (AA 511-580) (CF®555) (ABIN7875532)

Antigène: Glypican 3 (GPC3)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Glypican 3 est conjugé à/à la CF®555

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: SPM595

Détail du produit anti-Glypican 3 anticorps (CF®555)

Épitope: AA 511-580

Fonction: Glypican 3 Antibody

Purification: Protein G affinity chromatography

Immunogène: A recombinant fragment containing amino acids 511-580 from the human protein was used as the immunogen for the Glypican-3 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the Glypican 3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 500 µL at 0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the Glypican 3 antibody at 2-8oC, protected from light.

Détails sur Glypican 3

Antigène: Glypican 3 (GPC3)

Autre désignation: Glypican 3

Sujet: Glypican-3 (GPC3) is a glycosylphospatidyl inositol-anchored membrane protein, which may also be found in a secreted form. Anti-GPC3 has been identified as a useful tumor marker for the diagnosis of hepatocellular carcinoma (HCC), hepatoblastoma, melanoma, testicular germ cell tumors, and Wilms tumor and hepatoblastoma, with a low or undetectable expression in normal adjacent tissue. In patients with thyroid cancer, expression of GPC3 is dramatically enhanced in certain types of cancers: 100 % in follicular carcinoma and 70 % in papillary carcinoma. Expression of GPC3 in follicular carcinoma is significantly higher than that of follicular adenoma. In contrast, GPC3 is not expressed in anaplastic carcinoma.

UniProt: P51654

Pathways: Glycosaminoglycan Metabolic Process