Glutaminase anticorps (AA 516-545)

N° du produit ABIN7875535

Cet anticorps anti-Glutaminase Polyclonal Lapin (ABIN7875535) détecte spécifiquement Glutaminase dans WB, IF, FACS et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Glutaminase anticorps (AA 516-545) (ABIN7875535)

Antigène: Glutaminase (GLS)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glutaminase est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Glutaminase anticorps

Épitope: AA 516-545

Fonction: Glutaminase Antibody / GLS

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 516-545 from the human protein were used as the immunogen for the Glutaminase antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the Glutaminase antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Glutaminase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Glutaminase

Antigène: Glutaminase (GLS)

Autre désignation: Glutaminase

Sujet: Sahai (1983) demonstrated phosphate-activated glutaminase (EC 3.5.1.2) in human platelets. It is the major enzyme yielding glutamate from glutamine. Significance of the enzyme derives from its possible implication in behavior disturbances in which glutamate acts as a neurotransmitter (Prusiner, 1981). High heritability of platelet glutaminase was indicated by studies of Sahai and Vogel (1983) [PubMed 6682827] who found an intraclass correlation coefficient of 0.96 for monozygotic twins and 0.53 for dizygotic twins.

UniProt: O94925

Pathways: Feeding Behaviour, Dicarboxylic Acid Transport, L'effet Warburg