ERN2 anticorps (AA 517-919)

N° du produit ABIN7875536

Cet anticorps Lapin Polyclonal détecte spécifiquement ERN2 dans ELISA, WB et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour ERN2 anticorps (AA 517-919) (ABIN7875536)

Antigène: ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERN2 est non-conjugé

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-ERN2 anticorps

Épitope: AA 517-919

Fonction: IRE2 Antibody / ERN2

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids K517-P919) was used as the immunogen for the IRE2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the IRE2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the IRE2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur ERN2

Antigène: ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))

Autre désignation: IRE2

Sujet: IRE2/ERN2 induces translational repression through 28S ribosomal RNA cleavage in response to endoplasmic reticulum (ER) stress. This pro-apoptotic appears to play no role in the unfolded-protein response, unlike closely related proteins. Overexpression of IRE2/ERN2 activates both BiP and CHOP expression, and also leads to the development of programmed cell death. It has been suggested that Ern2 plays a role in multiple facets of the ER stress response in mammalian cells.

UniProt: Q76MJ5