LEMD3 anticorps (AA 535-852)
Aperçu rapide pour LEMD3 anticorps (AA 535-852) (ABIN7875610)
Antigène
Voir toutes LEMD3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 535-852
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Fonction
- MAN1 Antibody / LEMD3
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Purification
- Antigen affinity purified
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Immunogène
- An E.coli-derived human recombinant protein (amino acids H535-H852) was used as the immunogen for the MAN1 antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the MAN1 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the MAN1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- LEMD3 (LEM Domain Containing 3 (LEMD3))
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Autre désignation
- MAN1
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Sujet
- LEM domain-containing protein 3 (LEMD3), also known as MAN1, is an integral protein in the inner nuclear membrane (INM) of the nuclear envelope. It is encoded by the LEMD3 gene and was first identified after it was isolated from the serum of a patient with a collagen vascular disease. This locus encodes a LEM domain-containing protein. The encoded protein functions to antagonize transforming growth factor-beta signaling at the inner nuclear membrane. Two transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis.
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UniProt
- Q9Y2U8
Antigène
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