JUP anticorps (AA 556-745)

N° du produit ABIN7875724

Cet anticorps anti-JUP Monoclonal Souris (Clone 4C12D7) (ABIN7875724) détecte spécifiquement JUP dans WB, IF, FACS et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour JUP anticorps (AA 556-745) (ABIN7875724)

Antigène: JUP (Junction Plakoglobin (JUP))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp JUP est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 4C12D7

Détail du produit anti-JUP anticorps

Épitope: AA 556-745

Fonction: JUP Antibody / Junction Plakoglobin / Gamma Catenin

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids M556-A745) was used as the immunogen for the JUP antibody.

Isotype: IgG1

Information d'application

Indications d'application: Optimal dilution of the JUP antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the JUP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur JUP

Antigène: JUP (Junction Plakoglobin (JUP))

Autre désignation: JUP

Sujet: Junction plakoglobin (JUP), also known as gamma-catenin, is a protein that in humans is encoded by the JUP gene. It is a member of the catenin protein family and homologous to g-catenin, and it is mapped to 17q21.2. This gene encodes a major cytoplasmic protein that is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins. Meanwhile, JUP may have distinct roles in Wnt signaling and cancer via differential effects on downstream target genes.

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location