Recombinant ACTN2 anticorps (AA 557-692)

N° du produit ABIN7875729

L’anticorps anti-ACTN2 Monoclonal Lapin est utilisé pour la détection de ACTN2 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Recombinant ACTN2 anticorps (AA 557-692) (ABIN7875729)

Antigène: ACTN2 (Actinin, alpha 2 (ACTN2))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp ACTN2 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: ACTN2-7040R

Détail du produit anti-ACTN2 anticorps

Épitope: AA 557-692

Fonction: Recombinant Alpha Actinin 2 Antibody / ACTN2 / Sarcomeric Alpha Actinin

Purification: Protein A/G affinity

Immunogène: A portion of amino acids 557-692 from the human protein was used as the immunogen for the recombinant Alpha Actinin 2 antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant Alpha Actinin 2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the recombinant Alpha Actinin 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur ACTN2

Antigène: ACTN2 (Actinin, alpha 2 (ACTN2))

Autre désignation: Alpha Actinin 2

Sujet: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In non-muscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.

UniProt: P35609

Pathways: Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity