C1S anticorps (AA 560-589)

N° du produit ABIN7875782

Cet anticorps Lapin Polyclonal détecte spécifiquement C1S dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour C1S anticorps (AA 560-589) (ABIN7875782)

Antigène: C1S (Complement Component 1, S Subcomponent (C1S))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C1S est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-C1S anticorps

Épitope: AA 560-589

Fonction: C1S Antibody / Complement C1s subcomponent

Immunogène: A portion of amino acids 560-589 from the human protein was used as the immunogen for the C1S antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the C1S antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide and 50 % glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the C1S antibody at -20oC.

Détails sur C1S

Antigène: C1S (Complement Component 1, S Subcomponent (C1S))

Autre désignation: C1S

Sujet: C1S, also called Complement C1s subcomponent, is a serine protease enzyme that plays a significant role in the activation of the Complement system, which is a part of the innate immune system. C1S is a key component of the C1 complex, which is the first step in the Complement activation cascade. One of the main functions of C1S is to cleave C4 and C2 proteins, leading to the formation of the C3 convertase enzyme. This enzyme then cleaves C3 protein into two parts, C3a and C3b, which mediate various immune responses such as inflammation, opsonization, and cell lysis. Overall, the activation of the Complement system through C1S plays a critical role in enhancing the immune response and clearing pathogens from our bodies. In addition to its role in immune defense, C1S has also been implicated in other physiological processes such as inflammation, tissue repair, and development. Dysregulation of C1S activity has been linked to various diseases, including autoimmune disorders, inflammatory conditions, and infectious diseases.

UniProt: P09871

Pathways: Système du Complément