ACTN2 anticorps (AA 567-696)

N° du produit ABIN7875795

L’anticorps anti-ACTN2 Polyclonal Lapin est utilisé pour la détection de ACTN2 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IHC (p) et FACS.

Aperçu rapide pour ACTN2 anticorps (AA 567-696) (ABIN7875795)

Antigène: ACTN2 (Actinin, alpha 2 (ACTN2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACTN2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-ACTN2 anticorps

Épitope: AA 567-696

Fonction: ACTN2 Antibody / Alpha Actinin 2 / Sarcomeric Alpha Actinin

Purification: Affinity purified

Immunogène: An E. coli-derived human protein (amino acids E567-E696) was used as the immunogen for the ACTN2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the ACTN2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the ACTN2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur ACTN2

Antigène: ACTN2 (Actinin, alpha 2 (ACTN2))

Autre désignation: ACTN2

Sujet: Alpha-actinin 2 is a protein which in humans is encoded by the ACTN2 gene. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.

UniProt: P35609

Pathways: Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity