Recombinant Frataxin anticorps (AA 57-210)
Aperçu rapide pour Recombinant Frataxin anticorps (AA 57-210) (ABIN7875800)
Antigène
Voir toutes Frataxin (FXN) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Épitope
- AA 57-210
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Fonction
- Recombinant Frataxin Antibody / FXN (azide and preservative free)
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Purification
- Protein G affinity chromatography
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Immunogène
- Amino acids 57-210 from the human protein were used as the immunogen for this FXN antibody.
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Isotype
- IgG1, kappa
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Indications d'application
- Optimal dilution of the recombinant Frataxin antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store the recombinant Frataxin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Frataxin (FXN)
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Autre désignation
- Frataxin
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Sujet
- Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix suggesting that Frataxin is involved in mitochondrial iron homeostasis and possibly in iron transport. Frataxin has an alpha-beta fold consisting of two helices flanking an antiparallel beta sheet.
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UniProt
- Q16595
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Pathways
- Transition Metal Ion Homeostasis, Regulation of Cell Size
Antigène
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