Recombinant Frataxin anticorps (AA 57-210)

N° du produit ABIN7875801

L’anticorps anti-Frataxin Monoclonal Souris est utilisé pour la détection de Frataxin dans des échantillons de Humain. Il a été validé pour ELISA.

Aperçu rapide pour Recombinant Frataxin anticorps (AA 57-210) (ABIN7875801)

Antigène: Frataxin (FXN)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Frataxin est non-conjugé

Application: ELISA

Clone: RFXN-2124

Détail du produit anti-Frataxin anticorps

Épitope: AA 57-210

Fonction: Recombinant Frataxin Antibody / FXN

Purification: Protein G affinity chromatography

Immunogène: Amino acids 57-210 from the human protein were used as the immunogen for this FXN antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant Frataxin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the recombinant Frataxin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Frataxin

Antigène: Frataxin (FXN)

Autre désignation: Frataxin

Sujet: Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix suggesting that Frataxin is involved in mitochondrial iron homeostasis and possibly in iron transport. Frataxin has an alpha-beta fold consisting of two helices flanking an antiparallel beta sheet.

UniProt: Q16595

Pathways: Transition Metal Ion Homeostasis, Regulation of Cell Size