APOB anticorps (AA 592-689)

N° du produit ABIN7875924

L’anticorps anti-APOB Monoclonal Souris est utilisé pour la détection de APOB dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour APOB anticorps (AA 592-689) (ABIN7875924)

Antigène: APOB (Apolipoprotein B (APOB))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp APOB est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: APOB-4333

Détail du produit anti-APOB anticorps

Épitope: AA 592-689

Fonction: Apolipoprotein B Antibody / APOB

Purification: Protein G affinity chromatography

Immunogène: A portion of amino acids 592-689 from the human protein was used as the immunogen for the Apolipoprotein B antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the Apolipoprotein B antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Apolipoprotein B antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur APOB

Antigène: APOB (Apolipoprotein B (APOB))

Autre désignation: Apolipoprotein B

Sujet: Post-transcriptional editing of apolipoprotein B (apoB) mRNA is regulated by APOBEC1 (also designated human (or rat) small intestinal apolipoprotein B mRNA editing protein, HEPR or REPR) in hepatic cells to achieve a steady state proportion of edited and unedited RNA molecules. Two forms of apoB are known to circulate in the plasma of mammals. ApoB-100 is a protein primarily synthesized in the liver as a structural component of very low density lipoprotein particles. A truncated form of apoB-100, apoB-48, is synthesized in the small intestine and contains the amino-terminal 2,152 amino acids of the larger protein. This organ-specific partitioning of apoB production is the resultof RNA editing of a common apoB gene.

UniProt: P04114

Pathways: Lipid Metabolism