Recombinant CD35 anticorps (AA 600-900)

N° du produit ABIN7876035

L’anticorps anti-CD35 Monoclonal Lapin est utilisé pour la détection de CD35 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Recombinant CD35 anticorps (AA 600-900) (ABIN7876035)

Antigène: CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD35 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CR1-8833R

Détail du produit anti-CD35 anticorps

Épitope: AA 600-900

Fonction: Complement receptor 1 Antibody / CD35

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 600-900) from the human protein was used as the immunogen for the Complement receptor 1 antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the Complement receptor 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Complement receptor 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur CD35

Antigène: CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))

Autre désignation: Complement receptor 1

Sujet: CD35, complement receptor 1, is a cell membrane-bound, monomeric glycoprotein on numerous cell types including erythrocytes, leukocytes, glomerular podocytes, and follicular dendritic cells. The primary function of CD35 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. CD35 antigen is found on erythrocytes, B cells, a subset of T cells, monocytes, as well as eosinophils, and neutrophils. Anti-CD35 is considered a mature B-cell marker which labels follicular dendritic reticulum cells and tumors derived from such cells such as follicular dendritic cell tumor/sarcoma.

UniProt: P17927

Pathways: Système du Complément, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Endopeptidase Activity